Learning Objectives
          After completing this activity, the participant will demonstrate the ability to: 
- Assess the clinical and psychosocial implications caused by the effects of GHD and growth-related disorders
 
- Implement clinical practice guidelines for GHD and growth-related 
disorders that ensure early and accurate diagnoses, testing 
requirements, coding, treatment considerations, and follow-up for 
optimal patient outcomes 
  
- Employ pharmacoeconomic modeling and other decision support tools to appropriately invest resources on GH replacement therapy
 
- Provide accurate and appropriate counsel as part of the care team
  
- Provide appropriate care and counsel for patients and their families
  
   
                        
         Faculty
          
    Albert Tzeel, MD, MHSA, CPE, FACPE, FAAP 
Medical Director 
HumanaOne  
Milwaukee, Wisconsin
      
  
      
        Albert Tzeel, MD, MHSA, CPE, FACPE, FAAP
        Albert Tzeel, MD, MHSA, CPE, FACPE, FAAP is the National Medical Director for HumanaOne, based in Milwaukee, Wisconsin. In
 his current role, Dr. Tzeel functions as a member of the executive 
management team for the Individual Health Insurance Product. He
 provides clinical input and expertise to the development, 
implementation and actions of underwriting as well as strategic 
marketing of healthier risks. In addition, Dr. Tzeel creates clinical 
strategies coordinated with other clinical management processes in place
 throughout the company. Specifically, he functions as the internal 
subject matter expert on the topic of diabetes. Prior to his assuming 
the role with HumanaOne, Dr. Tzeel was the Regional Market 
Medical Officer for Humana's Wisconsin and Michigan markets. He is a 
Board Certified pediatrician. 
 
 
Dr. Tzeel joined Humana in March, 1999 as Medical Director for the Milwaukee market. Previously, he served as Associate Medical Director for the Health Alliance Plan in Detroit, Michigan. Dr.
 Tzeel earned his Medical Degree from the University of Michigan Medical
 School in Ann Arbor, MI and his Masters in Health Services 
Administration from the University of Michigan School of Public Health, 
also in Ann Arbor. He is a Certified Physician Executive, a
 Fellow of the American College of Physician Executives and a Fellow of 
the American Academy of Pediatrics. 
 
 
Dr. Tzeel represents Humana on numerous external committees including 
the Board of Directors of the Center for Health Value Innovation 
(www.vbhealth.org) and the Board of Advisors for the Wisconsin Health 
Information Exchange (www.whie.org). He had also been 
appointed to the Governance Committee of the Wisconsin Relay of 
Electronic Data (WIRED) for Health Board. Earlier, he served as the 
Chair of the Healthcare subcommittee of the Wisconsin Partnership on 
Activity and Nutrition. Dr. Tzeel is the author or co-author of multiple
 papers and books including "When to Call the Doctor" (Dalmatian Press, 
1999) and "The Encyclopedia of Children's Health and Wellness" (Facts on
 File, 2004). 
       
      
    
    
  Linda Bevington, RN, BSN, CPN 
Patient/Family Educator 
Family Learning Center 
Children's Hospital of Philadelphia 
Philadelphia, PA
      
  
      
        Linda Bevington, RN, BSN, CPN
        Linda Bevington, RN, BSN, CPN is a Patient Family 
Educator at Children's Hospital of Philadelphia (CHOP). She has over 15 
years experience in training patients and caregivers to use various 
growth hormone therapy devices. Ms. Bevington has served as faculty on 
several continuing nursing and patient education programs and recently 
presented a poster at the 28th Annual Pediatric Nursing 
Conference on the use of video instruction to improve caregiver 
education. Along with her colleagues from CHOP's Artificial Airway 
Advisory Group, she received the Health Care Education Association's 
Award for Excellence in Practice: Patient/Community Education for her 
work to optimize education for caregivers with children with a 
tracheotomy and ventilator being discharged to home care. 
       
      
    
      
    Pinchas Cohen, MD 
Professor and Chief of Endocrinology 
Mattel Children's Hospital 
David Geffen School of Medicine 
University of California, Los Angeles 
Los Angeles, CA
      
  
      
        Pinchas Cohen, MD
        Dr. Cohen graduated with highest honors in 1986 from 
the Technion Medical School in Israel, and trained in Pediatrics, 
Endocrinology and Diabetes at Stanford University until 1992. He
 was an Associate Professor and Program Director at the University of 
Pennsylvania and Children's Hospital of Philadelphia until 1998. He is 
currently a Professor and Chief of Endocrinology at Mattel Children's 
Hospital, David Geffen School of Medicine at the University of 
California, Los Angeles (UCLA). He is also the associate director of the
 UCSD/UCLA Diabetes/Endocrinology Research Center. He was inducted into 
both the Society for Pediatric Research and the American Pediatric 
Society. He is the recipient of Juvenile Diabetes 
Association, American Diabetes Association, Pediatric Diabetes & 
Endocrinology Society, Eli Lilly, CaPCURE, and Ross awards, and most 
recently, the American Pediatric Society Best Science Award. Dr. Cohen 
published over 250 papers focusing on diabetes, growth disorders, 
cancer, aging, GH/IGF biology and the emerging science of humanin and 
other mitochondrial peptides. He received grants from the 
National Institutes of Health (NIH), FDA, and various foundations 
including the Prostate Cancer Foundation. He recently received a 
EUREKA-Award and the NIH-Director-Transformative RO1-Grant. He serves on
 several NIH study sections and his editorial services include being an 
associate editor of Pediatric Research and a member of the editorial boards of Journal of Clinical Endocrinology and Metabolism, Endocrinology, and the Journal of GH and IGF Research,
 as well as being an executive officer of the GH Research society, the 
IGF Society and the Endocrine Society Steering Committee. 
       
      
    
     
     Terri H. Lipman, PhD, CRNP, FAAN 
Miriam Stirl Endowed Term Professor of Nutrition 
Professor of Nursing of Children 
University of Pennsylvania School of Nursing 
Philadelphia, PA
      
  
      
        Terri H. Lipman, PhD, CRNP, FAAN 
        Terri H. Lipman, PhD, CRNP, FAAN, is the Miriam Stirl
 Endowed Term Professor of Nutrition, a Professor of Pediatric Nursing 
at the University of Pennsylvania and the director of the Pediatric 
Acute/Chronic and Pediatric Oncology Nurse Practitioner Programs. She is
 a faculty member of the Center for Health Equities, associated faculty 
in the Center for Public Health Initiatives and a Distinguished Fellow 
in the Netter Center for Community Partnerships. She is the recipient of
 the Lindback Award for Distinguished Teaching. Dr. Lipman is also a 
pediatric nurse practitioner in the Division of Endocrinology and 
Diabetes at the Children's Hospital of Philadelphia.  
 
Dr. Lipman received her BSN from Temple University in Philadelphia, and 
her MSN, PhD and CRNP from the University of Pennsylvania. After 
receiving her master's degree she practiced as an advanced practice 
nurse at St. Christopher's Hospital for Children. Dr. Lipman serves on 
numerous professional committees. She is the co-chair of the 
Surveillance Committee for the Pennsylvania Diabetes Action Plan and has
 long been active in the PENS organization. She has served as Research 
Chair, Grant Director and is currently the editor of the PENS column in 
the Journal of Pediatric Nursing.  
 
Dr. Lipman has published widely and has given numerous national and 
international presentations. Her major areas of research have been the 
epidemiology of diabetes and assessment of growth of children. The 
Philadelphia Pediatric Diabetes Registry is one of only three 
longstanding such registries in the United States. She and Karen Hench, 
RN, MS, were co-principal investigators of a multicenter randomized, 
controlled trial evaluating growth assessment 
in primary care practices. That study, funded by the Genentech 
Foundation for Growth and Development and by PENS, was published in the Archives of Diseases in Childhood and the Journal of Pediatric Nursing
 and has received widespread coverage in the lay press. Dr. Lipman's 
current research interests include racial disparities in children with 
endocrine disorders, the effect of the economic distress on food choices
 in adolescents, and community based participatory research. Dr. 
Lipman's nurse practitioner students collaborated with inner city high 
school students to screen children in the community for diabetes risk 
factors. The students received a Mayoral Proclamation and Citations from
 Philadelphia City Council for their service to the community.  
       
      
    
     
     Mark E. Molitch, MD 
Professor of Medicine 
Endocrinology 
Northwestern University Feinberg School of Medicine 
Chicago, IL
      
  
      
        Mark E. Molitch, MD
        Dr. Molitch is an endocrinologist specializing in diabetes at Northwestern Memorial Hospital. He
 is also a Professor of Medicine in the Division of Endocrinology, 
Metabolism, and Molecular Medicine at the Northwestern University's 
Feinberg School of Medicine. His specialties include pathogenesis and 
treatment of pituitary tumors as well as the treatment of diabetic 
complications. Before earning his doctorate from the 
University of Pennsylvania, Dr. Molitch completed a fellowship with the 
University of California-Los Angeles Medical Center. He is board 
certified in the areas of endocrinology, diabetes and metabolism and 
internal medicine. Dr. Molitch is also devoted to serving the 
underprivileged people of Bolivia as cofounder of a clinic called Centro
 Medico Humberto Parra.    
 
In addition to editing eight books and journal volumes, Dr. Molitch has 
authored or coauthored more than 350 original papers, review articles, 
book chapters, case reports and other publications. For many years, Dr. 
Molitch was an Associate Editor of the Year Book of Endocrinology and is
 an Editor of the journal, Pituitary. In 1997, Dr. Molitch was named 
"Outstanding Physician Educator in the Field of Diabetes" by the 
American Diabetes Association. In 2006 he was elected to the Council of 
The Endocrine Society. He is currently Chair of the Clinical 
Endocrinology Update 2010 program committee of the Endocrine Society. 
       
      
    
    
      Nancy A. Nickman, PhD, RPh 
Professor of Pharmacotherapy 
Department of Pharmacotherapy 
University of Utah College of Pharmacy 
Salt Lake City, UT
      
  
      
        Nancy A. Nickman, PhD, RPh
        Dr. Nancy Nickman is a Professor of Pharmacotherapy 
and Presidential Teaching Scholar in the College of Pharmacy at the 
University of Utah. She received a Bachelor of Science in Pharmacy degree
 from the University of Montana and graduate degrees from the University
 of Minnesota in both Hospital Pharmacy (MS) and Social and 
Administrative Pharmacy (PhD). She also completed a two year ASHP 
Residency in Hospital Pharmacy at United and Children's Hospital in St. 
Paul, Minnesota (1982-1984). Nancy served as a tenured professor from 
1987-2001, and returned to the faculty as a Professor of Pharmacotherapy
 in 2004 after owning her own business for five years. In 1995, she was 
named a University of Utah Presidential Teaching Scholar (award merged 
in 1997 with the University of Utah Distinguished Teaching Award). Her 
teaching and research expertise includes patient-centered outcomes 
research to improve provision and quality of patient care based on 
application of industrial engineering and economic analyses. 
Publications and presentations include work sampling evaluations of 
institutional pharmacy services for redesign of structural and 
functional activities, pre-post analyses of the impact of technology on 
the practice of health professionals, simulated time-and-motion 
evaluations coupled with microcost analyses of issues related to 
medication preparation and administration, and simulated time-and motion
 analysis of devices intended for medication self-administration. 
       
      
     
          
        
      
            
  Jointly sponsored/coprovided by the Postgraduate Institute for Medicine and Impact Education, LLC 
www.impactedu.net             www.pimed.com 
              
 
The Managed Care Review Board™ – Analysis of Therapies for Growth Hormone Deficiency and Growth-Related Disorders 
 
 
  
Supported by an educational grant from Novo Nordisk, Inc. 
  
 
Estimated time to complete activity: 1.5 hours 
 
Target Audience 
    - Medical Directors and Pharmacy Directors from health plans,  
HMOs, integrated health systems, employers, quality organizations, and  
other managed care organizations (MCOs)
 
    - Managed care-affiliated care team members involved with patient 
 evaluation, education, and follow-up for growth/growth disorders  
including: physicians, pharmacists, registered nurses, and case managers
 
 
Special Offering 
Video demonstration of various recombinant human growth hormone (rhGH) administration devices by a nurse specialist.   
 
Statement of Need
The treatment of children with recombinant human growth  
hormone (rhGH) can be effective for increasing height toward  
normalization in all indications, particularly in children with growth  
hormone deficiency (GHD). Some studies have shown that children with  
idiopathic short stature (ISS) and GHD suffer from stress and other  
emotional and behavioral problems. Adults with GHD receiving rhGH  
therapy show improvements in body composition, quality of life, and  
surrogate markers for cardiovascular disease.    
 
 
The treatment of GHD and growth-related disorders present distinct challenges for MCOs, payers, and affiliated providers. Balancing resource allocation with patient safety and optimal clinical outcome is paramount to payers and patients alike. Informed
  decisions are needed about the optimal role of GH replacement therapy 
 so that patients who will benefit most are sure to receive it. This  
activity will address the educational needs of the target audience to  
enhance the health and well-being of many health plan patients, both  
children and adults, who suffer from GHD and growth-related disorders. 
 
 
Physician Accreditation Statement 
This activity has been planned and implemented in accordance 
with the Essential Areas and policies of the Accreditation Council for 
Continuing Medical Education through the joint sponsorship of 
Postgraduate Institute for Medicine and Impact Education, LLC. The 
Postgraduate Institute for Medicine is accredited by the ACCME to 
provide continuing medical education for physicians. 
 
 
  
Credit Designation 
The Postgraduate Institute for Medicine designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 
 
Pharmacist Accreditation Statement 
Postgraduate Institute for Medicine is accredited by the  
Accreditation Council for Pharmacy Education as a provider of continuing
  pharmacy education. 
 
 
Credit Designation 
Postgraduate Institute for Medicine designates this 
continuing education activity for 1.5 contact hours (1.5 CEUs) of the 
Accreditation Council for Pharmacy Education.  
(Universal Activity Number – 0809-9999-13-200-H01-P) 
 
Type of Activity: Application 
 
For Pharmacists: Upon receipt of the completed 
activity evaluation form, transcript information will be available at 
www.mycpemonitor.net within 4 weeks. 
 
Nursing Continuing Education 
 
Credit Designation 
This educational activity for 1.5 contact hours is provided by Postgraduate Institute for Medicine. 
 
Accreditation Statements 
 Postgraduate
  Institute for Medicine is accredited as a provider of continuing  
nursing education by the American Nurses Credentialing Center's  
Commission on Accreditation. 
 
 
 
 
  
Disclosure of Conflicts of Interest 
Postgraduate Institute for Medicine (PIM) requires 
instructors, planners, managers and other individuals who are in a 
position to control the content of this activity to disclose any real or
 apparent conflict of interest (COI) they may have as related to the 
content of this activity. All identified COI are thoroughly vetted and 
resolved according to PIM policy.  PIM is committed to
 providing its learners with high quality CME activities and related 
materials that promote improvements or quality in healthcare and not a 
specific proprietary business interest of a commercial interest. 
  
The faculty reported the following 
financial relationships or relationships to products or devices they or 
their spouse/life partner have with commercial interests related to the 
content of this CME activity: 
  
    
        
            | 
             Name of Faculty or Presenter 
             | 
            
             Reported Financial Relationship 
             | 
         
        
            | 
             Albert Tzeel, MD, MHSA, CPE, FACPE, FAAP 
             | 
            
             Consulting Fees: Amylin Pharmaceuticals Inc. 
             | 
         
        
            | Linda Bevington, RN, BSN, CPN | 
            No financial interest/relationships relating to the topic of this activity | 
         
        
            | Pinchas Cohen, MD | 
            Consulting Fees: Novo Nordisk, Inc. | 
         
        
            | Terri H. Lipman, PhD, CRNP, FAAN | 
            Consulting Fees: Roche, Inc. | 
         
        
            | Mark E. Molitch, MD | 
            
             Consulting Fees: Novo Nordisk, Inc. 
            Contracted Research: Novo Nordisk, Inc. and Eli Lilly and Company | 
         
        
            | 
             Nancy A. Nickman, PhD, RPh 
             | 
            Contracted Research: Amgen Inc. and Novartis Pharmaceuticals Corporation 
             | 
         
    
 
  
The planners and managers reported 
the following financial relationships or relationships to products or 
devices they or their spouse/life partner have with commercial interests
 related to the content of this CME activity: 
  
The following PIM planners and managers, Laura Excell, ND, 
NP, MS, MA, LPC, NCC, Trace Hutchison, PharmD, Samantha Mattiucci, 
PharmD, CCMEP, Jan Schultz, RN, MSN, CCMEP, and Patricia Staples, MSN, 
NP-C, CCRN, hereby state that they or their spouse/life partner do not 
have any financial relationships or relationships to products or devices
 with any commercial interest related to the content of this activity of
 any amount during the past 12 months.  
  
    
        
            | 
             Planner: 
            Steven Casebeer, MBA 
             | 
            
              
            Has nothing to disclose. 
             | 
         
    
 
  
Method of Participation and Request for Credit 
There are no fees for participating and receiving CME credit 
for this activity. During the period May 30, 2013 through November 30, 
2014, participants must 1) read the learning objectives and faculty 
disclosures; 2) study the educational activity; 3) successfully complete
 the embedded questions within the activity; 4) and complete the 
evaluation form. Upon completion of the full CME/CE activity, your 
certificate will be made available immediately to download and print. 
 
 
For Pharmacists: Upon receipt of the completed activity 
evaluation form, transcript information will be available at 
www.mycpemonitor.net within 4 weeks. 
 
Media 
Internet 
 
  
Disclosure of Unlabeled Use 
This educational activity may contain discussion of published
 and/or investigational uses of agents that are not indicated by the 
FDA. The planners of this activity do not recommend the use of any agent
 outside of the labeled indications.   
  
The opinions expressed in the educational activity are those 
of the faculty and do not necessarily represent the views of the 
planners. Please refer to the official prescribing 
information for each product for discussion of approved indications, 
contraindications, and warnings. 
  
Disclaimer   
Participants have an implied responsibility to use the newly 
acquired information to enhance patient outcomes and their own 
professional development. The information presented in this activity is 
not meant to serve as a guideline for patient management. Any 
procedures, medications, or other courses of diagnosis or treatment 
discussed or suggested in this activity should not be used by clinicians
 without evaluation of their patient's conditions and possible 
contraindications and/or dangers in use, review of any applicable 
manufacturer's product information, and comparison with recommendations 
of other authorities. 
  
Hardware/Software Requirements 
Google Chrome for Windows, Mac, or Linux 
Internet Explorer 7.0+ for Windows 
Mozilla 1.4+ for Windows, Mac, or Linux 
Firefox 3.5+ for Windows, Mac, or Linux 
Safari 4.0+ for Mac 
 
Fee Information 
There is no fee for this educational activity. 
  
Questions
 If you have any questions, please call (215) 619-8812 or email MCRB@impactedu.net 
 
  
  
        
     
      
    
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